AHEAD (Advancing Head and Neck Cancer Early Detection Research) (U01 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to accelerate translation of research to improve early detection of head and neck cancers (HNC). This FOA seeks applications that focus on early detection of HNC by applying molecular, cellular, and multi-omics signatures to clinical studies for differentiating benign from premalignant lesions, and identifying prognostic signatures on the transformation from premalignant to malignant lesions. Better understanding of the molecular characteristics of dysplastic lesions and early recurrence are needed for improving lesion classification relevant to predicting cancer progression, which could have a significant impact on cancer prevention and treatment optimization.