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The membership of the Chao Family Comprehensive Cancer Center represents a broad range of scientific and clinical disciplines working together to advance discoveries in the etiology, causes, prevention, diagnosis and treatment of cancer through the translational pipeline.

Research Programs

CFCCC members, who are drawn from more than 32 departments across six schools at UC Irvine, are organized into four research programs, providing an interactive and collaborative infrastructure for cancer discovery, clinical investigation including early phase and investigator-initiated trials, and population-based cancer research:

Disease-Oriented Teams (DOTs)

The DOTs are a critical component of the CFCCC translational research effort, bringing together clinical researchers in different anatomic cancer areas with basic and translational scientists to manage the clinical trials portfolios, develop and bring forward new clinical trial concepts, and foster the translation of Cancer Center discoveries (new targets, biomarkers, drugs, agents, devices, and interventions) through the pipeline into the clinic.

Shared Resources

CFCCC supports a variety of high quality core facilities that provide expert support services and state-of-the-art equipment to its members:

Clinical Trials

CFCCC members are actively engaged in clinical research, conducting close to 200 clinical trials. Supporting this effort is the Sue and Ralph Stern Center for Cancer Clinical Trials and Research, which provides a centralized resource for clinical investigators on all activities related to the successful conduct of clinical trial research.


CFCCC's members are the cornerstone of its mission to alleviate the burden of cancer and provide the best possible care for patients and their families by integrating world-class research, prevention and state-of-the-art diagnostics, treatment and rehabilitation programs.