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Cancer Prevention, Outcomes & Survivorship Program (CPOS)

The overall goal of the CPOS program is to foster and facilitate research designed to identify and reduce cancer risk and improve cancer outcomes throughout the disease continuum. To accomplish this goal a broad, interdisciplinary membership is required. Our membership includes geneticists, epidemiologists, social and behavioral scientists, clinical oncology scientists, biostatisticians, health economics/services and public health researchers.

1)    Develop and test strategies to reduce cancer susceptibility in high risk populations.

Chemoprevention scientists have continued their rigorous tests of hypothesis-driven investigator initiated trials which included intra- and inter-programmatic collaborations between clinical investigators, basic scientists, and quantitative researchers. This well-developed area of research continues to benefit from programmatic collaborations which have yielded national studies with translational endpoints. More recently, social and behavioral scientists have received support to examine factors associated with adolescent nicotine uptake, including marketing, social networks, and biomarker correlations to ADHD. 

2)    Identify factors that assess disease and treatment outcomes.

Inter-programmatic collaborations have, for example, led to discovery of a genetic panel which can predict treatment outcome for prostate cancer patients, and patient-reported data can predict mortality, poor function and hospitalizations in these patients. CPOS will continue to foster new collaborations to innovative approaches to evaluation of treatment type, costs, and decision-making as it affects cancer patients.

3)    Test innovative interventions to improve cancer control and quality of life for cancer survivors.

The CPOS interdisciplinary collaborative teams of clinical, behavioral and basic scientists have formed inter- and intra-programmatic collaborations to provide interventions for vulnerable cancer survivor populations. CPOS is working with new cancer center leadership to identify promising translational approaches which have relevance to our catchment area, and beyond.

The Cancer Prevention, Outcomes and Survivorship Program continues to benefit from the established chemoprevention and genetic epidemiology science legacies, while simultaneously experiencing an infusion of transdisciplinary collaborations created to improve cancer outcomes and survivorship. Taken together, this robust, growing membership will strengthen our knowledge base, and cancer care, within our community.


  Christine McLaren, Ph.D.   Lari Wenzel, Ph.D.