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Research Title

Investigator

Program Area

Feasibility of a Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Hispanic Men with Testicular Cancer

Hoyt, Michael

Cancer Control

Novel Inhibitors of phosphoinositide 3-kinase (PI3K) that target scaffold protein-mediated interactions

Bardwell, Lee

Systems, Pathways & Targets

Neoadjuvant combination therapy with Cabozantinib and Nivolumab in patients with muscle-invasive urothelial carcinoma of the bladder who are Cisplatin-eligible and are candidates for radical cystectomy

Mar, Nataliya

Systems, Pathways & Targets

A Randomized Clinical Trial to Assess the Impact of a Remotely Administered Mediterranean Diet Intervention on Symptom Burden and Inflammatory Cytokines in Myeloproliferative Neoplasm

Fleischman, Angela

Systems, Pathways & Targets

Pilot study of the safety and feasibility of immediate postoperative chemotherapy in patients with metastatic invasive colonic adenocarcinoma

Jafari, Mehraneh Dorna

Cancer Control

Phase 2 Study of cabozantinib combined with ipilimumab/nivolumab and transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC) who are not candidates for curative intent treatment

Dayyani, Farshid

Systems, Pathways & Targets

Goal Directed Intervention for Adolescent Cancer Survivors

Fortier, Michelle

Cancer Control

Clock-dependent inflammatory and metabolic alterations in colorectal cancer

Masri, Selma

Systems, Pathways & Targets

Dissecting MAP4K kinases in cancer development and therapy

Wang, Wenqi

Systems, Pathways & Targets

Developing the Next Generation Antibody Drug Conjugates

Weiss, Gregory

Biotechnology, Imaging & Drug Development

Melanoma Screening and Staging with a Fiber Optical Device

Hedde, Per Niklas

Biotechnology, Imaging & Drug Development

The burgeoning cannabis industry and availability of cheap tobacco in Orange County, CA

Timberlake, David

Cancer Control

Restoring p53 activity in human cancer

Qiao, Feng

Systems, Pathways & Targets

Pilot study for evaluating the multiphoton microscopy potential for non-invasive, early diagnosis of melanoma

Kelly, Kristen

Biotechnology, Imaging & Drug Development

Factors Associated with Helicobacter Pylori Screening and Treatment among High-Risk Asians in Orange County: Mixed-Methods Research to Examine Stomach Cancer Disparity

Lee, Sunmin

Cancer Control

Research Title

Investigator

Program Area

A mechanistic study of age-dependent gender difference in melanoma risk

Liu-Smith, Feng

Cancer Control

Development and Testing of a Mobile Application for Young Adults with Cancer

Hoyt, Michael

Cancer Control

A Phase 1b study of TAS102 in combination with irinotecan in patients with advanced gastric and gastroesophageal adenocarcinoma

Dayyani, Farshid

Systems, Pathways & Targets

Experimental Therapeutics for Primary Pediatric Brain Tumors

Plant, Ashley

Biotechnology, Imaging & Drug Development

A phase I study of pitavastatin in combination with venetoclax for chronic lymphocytic leukemia (CLL) or acute myeloid leukemia (AML)

Brem, Elizabeth

Systems, Pathways & Targets

Control of B cell survival & transformation by the eIF4F translation initiation complex

Fruman, David

Systems, Pathways & Targets

True multi-modal image-guided intervention system

Nouizi, Farouk

Biotechnology, Imaging & Drug Development

UHRF1 as a therapeutic target for osteosarcoma

Benavente, Claudia

Systems, Pathways & Targets

Molecular mechanism of APOBEC3B-Mediated Mutation Shower in Ovarian Cancer

Buisson, Remi

Systems, Pathways & Targets

Advancing Oro-Pharyngeal Cancer Screening and Diagnosis to Overcome Disparities and Improve Control and Outcomes

Wilder-Smith, Petra

Biotechnology, Imaging & Drug Development

Single-cell transcriptome analysis of human Merkel Cell Carcinoma heterogeneity by single-cell RNA sequencing

Gao, Ling

Biotechnology, Imaging & Drug Development

Role of Phosphatase Methylation in One-Carbon Metabolism and Cancer

Kaiser, Peter

Systems, Pathways & Targets

The relationship between the gut microbiome and the efficacy of immune checkpoint inhibitors in patients with gynecologic malignancy

Tewari, Krishnansu

Cancer Control

Improving Depression Screening in a Multi-ethnic Cancer Population

Wenzel, Lari

Cancer Control

Macropinocytosis drives anabolism and drug resistance in breast cancer

Edinger, Aimee

Biotechnology, Imaging & Drug Development

DNA methylation markers for exposures to BPA and related compounds and breast cancer risk

Park, Hannah Lui

Cancer Control

Research Title

Investigator

Program Area

Identifying the anti-neoplastic targets of SH-BC-893

Edinger, Aimee

Biotechnology, Imaging & Drug Development

Analysis of Hippo signaling in breast cancer development

Wang, Wenqi

Systems, Pathways & Targets

Feasibility of a Family Focused Intergenerational Social Media Intervention for Orange County Vietnamese Families to Increase Preventive Cancer Screenings

Hopfer, Suellen

Cancer Control

RhoJ Inhibitors- A Novel Treatment for Early Stage Melanoma

Ganesan, Anand

Biotechnology, Imaging & Drug Development

Modulation of the Immune Response Against Metastatic Melanoma Using CD47 Blocking Antibodies

Boiko, Alexander

Systems, Pathways & Targets

Pilot study of mirtazapine for the dual treatment of depression and temozolomide-induced nausea and vomiting (CINV) in newly-diagnosed glioma patients

Bota, Daniela

Biotechnology, Imaging & Drug Development

Repurposing statins to enhance efficacy of BH3 mimetics in multiple myeloma

"Brem, Elizabeth
Fruman, David"

Systems, Pathways & Targets

Circadian Metabolic Deregulation of Colorectal Cancer

Masri, Selma

Systems, Pathways & Targets

Immunotherapeutic’s targeting altered N-glycosylation in cancer

Demetriou, Michael

Biotechnology, Imaging & Drug Development

Feasibility Study of a Mediterranean Diet Intervention to Reduce Inflammatory Cytokines in Patients with Myeloproliferative Neoplasms

Fleischman, Angela

Systems, Pathways & Targets

Pilot Study of the Safety and Feasibility of Immediate Adjuvant Chemotherapy in Patients with Invasive Colonic Adenocarcinoma

Pigazzi, Alessio

Systems, Pathways & Targets

Glutamine supplementation deters melanoma tumor growth via epigenetic reprogramming

Kong, Mei

Systems, Pathways & Targets