Steve Cramer MD, David Reinkensmeyer PhD, Mark Bachman PhD
Telerehabilitation to Reduce Disability After Stroke
This proposal brings together a team of a neurologist, an electrical/biomedical engineer, and a mechanical/biomedical engineer to develop technology and study how technology can be used to improve the delivery and efficacy of rehabilitation following a stroke. This team plans to develop, manufacture, and study a number of innovative low-cost sensor and game technologies that empower patients to participate in a rehabilitation regimen more effectively while providing quantitative information to healthcare specialists. The work will focus on generating preliminary data on technology-assisted rehabilitation using prototypes developed by the team.
School of Medicine • School of Engineering • School of Engineering
Krishnansu Tewari MD, FACOG, FACS; David Fruman PhD;
Robert Edwards PhD
Molecular Analysis of Alterations of the PI3K/AKT/mTOR Pathway in Lynch Syndrome- Associated Endometrial Cancer With Clinicopathologic Correlation
In Lynch syndrome (hereditary non-polyposis colon cancer), endometrial cancer is the most common gynecologic malignancy. Advanced and/or recurrent disease remains virtually incurable. The researchers will search for mutations (i.e. genetic aberration) in an important endometrial cancer molecular pathway called the PI3K/AKT/mTOR pathway. Identification of these mutations can lead to early diagnosis and enhanced survival in patients with Lynch syndrome-associated endometrial cancer.
School of Medicine • School of Biological Science • School of Medicine