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Cancer Center Members Among Recipients of the Third Annual Dean's Triumvirate Grant Awards

The Triumvirate Grant was created by Dean Ralph Clayman in 2010 to encourage novel collaborations among clinical and basic science researchers from the UC Irvine School of Medicine and other UC Irvine schools and programs. Cancer Center members are bolded below and include the following:

Steve Cramer MD, David Reinkensmeyer PhD, Mark Bachman PhD
Telerehabilitation to Reduce Disability After Stroke
Amount: $50,000

This proposal brings together a team of a neurologist, an electrical/biomedical engineer, and a mechanical/biomedical engineer to develop technology and study how technology can be used to improve the delivery and efficacy of rehabilitation following a stroke. This team plans to develop, manufacture, and study a number of innovative low-cost sensor and game technologies that empower patients to participate in a rehabilitation regimen more effectively while providing quantitative information to healthcare specialists. The work will focus on generating preliminary data on technology-assisted rehabilitation using prototypes developed by the team.

School of Medicine • School of Engineering • School of Engineering

Krishnansu Tewari MD, FACOG, FACS; David Fruman PhD;
Robert Edwards PhD
Molecular Analysis of Alterations of the PI3K/AKT/mTOR Pathway in Lynch Syndrome- Associated Endometrial Cancer With Clinicopathologic Correlation
Amount: $15,000

In Lynch syndrome (hereditary non-polyposis colon cancer), endometrial cancer is the most common gynecologic malignancy. Advanced and/or recurrent disease remains virtually incurable. The researchers will search for mutations (i.e. genetic aberration) in an important endometrial cancer molecular pathway called the PI3K/AKT/mTOR pathway. Identification of these mutations can lead to early diagnosis and enhanced survival in patients with Lynch syndrome-associated endometrial cancer.

School of Medicine • School of Biological Science • School of Medicine