Please send pilot project/seed grant, bridge funding and PSDM support applications to:
101 The City Drive
Bldg 56, Room 214
Orange, CA 92868
CCSG Pilot Project Funds e.g., Seed Grants allow centers to take risks; strengthen weaker scientific areas; and provide scientists the opportunity to explore innovative ideas, new collaborations and new technologies. These funds can be administered flexibly--dispensed centrally by the director and senior leaders to achieve broad strategic objectives. We make these funds accessible to all applicable areas of research, including laboratory, clinical, prevention, control, behavioral and population research for projects of relatively short duration (i.e., 1-2 years). They have been awarded to both new and established member and have been used for studies preparatory to the development of an application for independent peer-reviewed support, or to take maximum advantage of a unique research opportunity or nurture an innovative idea. These funds stimulate high priority research areas in the CFCCC, explore new directions for our Programs, and encourage cross-disciplinary translational research. Applications which support small, hypothesis-driven early clinical trials of an exploratory nature are also particularly encouraged.
The merit descriptors for review includes considerations such as the following:
The UCI Chao Family Comprehensive Cancer Center announces the availability of intramural funds to sustain cancer-related research projects that have recently lost, or face losing, extramural funding. Requests that provide evidence of a reasonable chance of funding upon resubmission of a recently reviewed application will receive a higher priority. Priority approvals will include CA designated grants from NCI, and A1 or A2 resubmissions with a priority score within 10% (prior NIH recipients) or 15% (first time applications for RPG funding) of the current payline (or if not, percentile score less than 200).
To be considered as a "peer reviewed, funded project," the responsible funding agency or organization should meet the general NIH standards of peer review and funding. These include meeting three criteria: (1) a peer review system which primarily uses external reviewers and is free of conflict of interest; (2) a ranking or rating system in the review process based on the scientific merit of the proposed research; and (3) a funding system based primarily on the peer review ranking or rating of the research applications.
Bridge support is intended for junior faculty/PIs (all series), although senior faculty/PIs are eligible to apply. A PI is eligible for the Bridge funding provided he or she meets the following requirements:
Exceptions to eligibility may be made by the Director under unusual circumstances.
Awards will be made in consultation with the Senior Leadership Committee and approved by the Director. Consideration will be given to need, assessment and the strength of the overall research program. To evaluate applications for Bridge Funding, the CFCCC requests the following:
Awards will be competitive and all applications may not be funded.
Protocol-specific data management (PSDM), also referred to as protocol-specific research support, is essential support for selected early phase trials conducted by investigators at the CFCCC. Development of hypothesis-driven, investigator-initiated (HDII) trials has been a major focus of the CFCCC in recent years. We have previously reported our success in increasing both the number of HDII trials and patient accrual to these trials, especially those that include a therapeutic intervention. Availability of personnel support through PSDM funding from the Cancer Center Support Grant, 5P30CA062203-16, has been a major factor contributing to the development and execution of these trials.
To qualify for PSDM support through the CFCCC, a trial must have the following characteristics:
Requests are reviewed by the Clinical Research Advisory Council to insure compliance with the basic requirements as outlined above. If multiple requests are being reviewed, they are prioritized based on priority needs for the CFCCC. Therapeutic trials are generally given preference but other types of intervention trials (prevention, for example) can be considered for PSDM support. Trials that are likely to generate preliminary data that will form the basis for future extramural funding of larger trials are specifically encouraged. Purely correlative trials are generally not considered. If funding is recommended at this level, review of finances and availability of funds for the relevant funding cycle determine the level of funding allocated. PIs are encouraged to solicit matching funds from other extramural sources for specific trials in order to leverage the PSDM dollars.