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About Southern California Chemoprevention Consortium Clinical Trials

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The SCCC coordinates Phase I and Phase II clinical trials designed to prevent cancers of the skin, colon, liver, and pancreas.  The purpose of a clinical trial is to test new agents in people with cancer or people who are at risk for developing a cancer.  The goal of the SCCC is to conduct clinical trials to find ways to prevent cancer from developing in people who are at risk of developing cancer.

As defined by the National Cancer Institute ( http://clinicaltrials.gov/ct2/info/understand): Clinical trials are conducted in phases.  The trials at each phase answer a different question and help researchers answer different questions:

In Phase I trials, researchers test an experimental drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase II trials, the experimental study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

The SCCC has completed four clinical trials evaluating new treatment strategies in the colon, liver, pancreas and skin. The results of those trials are available by following this link.

Currently there are two clinical trials open for participant recruitment:

  1. Enrolling participants with a history of colon cancer or colon adenomas (Erlotinib/Colon)
  2. Enrolling participants with a history of colorectal adenomas and elevated body mass index (Metformin/Colon)

If you are interested in participating in any of our open clinical trials, please contact the SCCC Operations Office for additional information.

SCCC Administrative Office
101  The City Drive South
Bldg 56
Orange, CA 92868
Phone: 888-456-7067
FAX: 714-456-7031
Email: SCCC.ASSIST@uci.edu