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The Mary Kay Foundation - Translational Research Grant Application

Internal Deadline:
Wednesday, December 5, 2018, end of day
Sponsor deadline: February 8, 2019

Award Amount:
$100K total costs over 2 years (up to 15% indirect costs)

# of applications allowed:
One (1) application permitted from UC Irvine

Download the RFP

The Mary Kay Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research in ovarian, uterine, breast or cervical cancer. Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. The Foundation is pleased to invite your institution to submit one grant proposal.

UC Irvine faculty (assistant, associate or full professors) with PI eligibility

To Apply:
Please submit the following as a single PDF to bmcclend@uci.edu by end of day, Wednesday, December 5, 2018

  • Cover Sheet: Include project title, your name, title, department, contact information, email address
  • Research proposal: 2 page research project description (illustrations & references not included in page total)
  • NIH-format biosketch
  • Other support: List of ALL other support, current AND pending (list name of sponsor, amount and term of funding)

Damon Runyon Cancer Research Foundation - 2018 Damon Runyon Clinical Investigator Award

Internal Deadline
December 12, 2018, end of day
Sponsor deadline: February 1, 2019

Amount of Funding:
$200,000 per year for 3 years (no indirect costs are provided)
The Damon Runyon Cancer Research Foundation will pay up to $100,000 of any qualifying medical school debt still owed by the awardee.

# of applications allowed:
Five (5) applications permitted from UC Irvine


The Damon Runyon Clinical Investigator Award supports independent young physician-scientists conducting disease-oriented research that demonstrates a high level of innovation and creativity. The goal is to support the best young physician-scientists doing work aimed at improving the practice of cancer medicine. The program is specifically intended to provide outstanding young physicians with the resources and training structure essential to becoming successful clinical investigators. The goal is to increase the number of physicians capable of moving seamlessly between the laboratory and the patient’s bedside in search of breakthrough treatments.


  • Candidates holding or awarded R01s at the time of application are not eligible to apply.
  • Must hold an independent Assistant Professor position or equivalent.
  • Must hold an MD or MD/PhD degree from an accredited institution and apply within the first five (4) years of initial faculty appointment (cut-off date July 2014). Adjuncts or acting positions are not eligible.
  • Must be a US citizen or permanent legal resident.
  • Must commit to spending 80% of time conducting research.
  • In rare unique circumstances, the CIA Review Committee may consider an applicant with a very modest reduction of 80% protected time if their Department Chair can provide a compelling reason explaining why a waiver of the 80% requirement should be granted, what percentage of effort will be guaranteed, and what safeguards will be put in place to make sure the individual’s research will not be compromised by their clinical/administrative activities.
  • Must apply in conjunction with a Mentor who is established in the field of clinical translational cancer research, cancer prevention and/or epidemiology and can provide the critical guidance needed during the period of the award. No more than two Damon Runyon Clinical Investigators will be funded to work with the same Mentor at any given time.
  • Only one application will be accepted from a mentor per review session (including co-mentorships).
  • Candidates may apply up to three times during this eligibility period.
  • Must have completed sub-specialty training, be U.S. board-eligible and hold a valid, active medical license at the time of application.

Other Restrictions:

  • Investigators may receive funding from other sources to support their research. However, no other physician-scientist mentored career development award from a private source (non-federal government) may be held concurrently with the Clinical Investigator Award.
  • Physician-scientist career development awards from the federal government including the National Institutes of Health (e.g., K-08, K-12, K-23), the Department of Defense, and the U.S. Department of Veterans Affairs are allowed.
  • Scientific or budgetary overlap with other funded projects is not allowed. Therefore, it is critical that all current and pending grant support for your research be reported to the Foundation and the relationship of that support to the Damon Runyon funded project be explained.
  • Examples of awards that cannot be held concurrently with the Damon Runyon Clinical Investigator Award include (but are not limited to):
    • AACR-Career Development Award
    • American Cancer Society-Mentored Research Scholar Grants in Applied and Clinical Research
    • Conquer Cancer Foundation (ASCO)-Career Development Award
    • Burroughs Wellcome Fund-Career Awards for Medical Scientists
    • Doris Duke Charitable Foundation-Clinical Scientist Development Award
    • Howard Hughes Medical Institute-Physician-Scientists Early Career Award, Early Career Scientist Competition
    • Leukemia and Lymphoma Society-Career Development Program, Scholar Awards

Definition of Clinical Research:

  • Patient-oriented research: Research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator directly interacts with human subjects. This area of research includes: patient-based studies of mechanisms of human disease, diagnostic and therapeutic interventions, clinical trials and development of new technologies for the detection, treatment and prevention of human cancers.
  • Epidemiologic and behavioral studies.
  • Outcomes research and health services research.
  • Excluded from this definition are in vitro studies that utilize human tissues but do not deal directly with patients. In other words, clinical or patient-oriented research is research in which it is necessary to know the identity of the patient(s) from whom the cells or tissues under study are derived.
  • Preference will be given to research that adheres to the “Handshake Rule,” meaning that the physician will conduct research studies that directly involve patients.

Selection Criteria:

  • Excellence of the applicant and mentor.
  • Innovation, creativity, quality and originality of the research proposal.
  • The commitment of the mentor and institution to the development and training of the applicant as a skilled clinical research investigator.
  • Evidence of the applicant’s commitment to clinical translational and/or cancer prevention research and their ability to apply advances in laboratory research to clinical problems.
  • Importance of the proposed research to the field of cancer and/or cancer prevention.
  • Adherence of the proposal to the definition of clinical research as set out on in the guidelines.
  • Adherence to the “Handshake Rule.”

To Apply:
Please send the following as a single PDF to ogawakh@uci.edu by end of day, Wednesday, December 12, 2018:

  • Cover Sheet: Include project title, your name, title, department, contact information, email address
  • Research proposal: 2 page scientific abstract/research proposal (illustrations & references not included in page total)
  • NIH-format biosketch
  • Other support: List of ALL other support, current AND pending (list name of sponsor, amount and term of funding)
  • Statement of support signed by the mentor and department/division chair that confirms that the nominee can commit 80% of their professional effort to the conduct of research and research career development.